A Case and Cranial MRI Characteristics of Progressive Supranuclear Palsy by Oğuzhan Gümüştaş in Trends in Ophthalmology Open Access Journal (TOOAJ)- Lupine Publishers Progressive supranuclear palsy (PSP) is a neurodegenerative disease described by vertical supranuclear gaze paralysis, axial rigidity and postural instability involving falls in the early stage of the disease. Imaging studies present brain atrophy in especially midbrain, premotor cortex, basal ganglia and thalamus. There is no bioindicator of the disease although it is clinically identified. PSP is also classified as tauopathy. However, no specific indicator for tau protein could be identified. Hence, imaging findings, especially midbrain atrophy, functions as a biomarker in clinical practice and determination of disease prognosis. It has been shown that midbrain atrophy has a diagnostic value for PSP accompanied with the finding of “hummingbird” or “penguin” encountered by magnetic resonance imaging (MRI). For more Lupine publishers open access journals please visit our websitehttps://lupinepublishers.com/index.php For more Ophthalmology journal impact factor articles click herehttps://lupinepublishers.com/ophthalmology-journal/ For more information click below linkhttps://lupinepublishers.com/ophthalmology-journal/fulltext/a-case-and-cranial-mri-characteristics-of-progressive-supranuclear-palsy.ID.000128.php https://lupinepublishers.com/ophthalmology-journal/pdf/TOOAJ.MS.ID.000128.pdf
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