Abstract
A case of severe acute corneal hydrops with keratoconus associated with Down syndrome described in a 16-year-old male patient presented with a sudden unilateral painful visual loss in his left eye. The anterior segment of his left eye showed a severe diffuse edematous ectasia of acute corneal hydrops. Eye rubbing of his left eye was observed. Continued gradual improvement in his visual acuity and a central corneal scar were detected.
Introduction
Down’s syndrome is frequently associated with keratoconus, a chronic non-inflammatory disorder which is characterized by progressive thinning of the cornea leading to scarring and progressive stromal thinning. Its incidence in Down’s syndrome has been reported up to 15% [1]. Acute corneal hydrops is characterized by marked stromal edema due to a tear in Descemet membrane (DM) which permits aqueous to enter the corneal stroma and epithelium [2-3].
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